Process for 1,4-dihydropyridine compounds using a titanamine cat

Details Process for 1,4-dihydropyridine compounds using a titanamine cat Process for 1,4-dihydropyridine compounds using a titanamine cat

1986-02-12

1988-10-25

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544124, 544216, 544333, 544364, 544365, 544405, 546193, 546194, 546257, 546271, 546275, 546276, 546278, 546279, 546280, 546281, 546283, 546284, 546277, 546321, C07D21102, C07D21190, C07D40104, C07D41304

Patent

active

047805382

ABSTRACT:
A process for the preparation of 1,4-dihydropyridine compounds, especially N-substituted 1,4-dihydropyridine compounds, is disclosed. The compounds are useful as cardiovascular agents and also as starting materials for the preparation of certain cyclized compounds which have properties as calcium entry blockers.

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Palecek, J. et al., Z. Chem., 14, 308-309 (1977).
Palecek, J. et al., Collection Czechoslouak Chem. Comm. 48, 608-16 (1983).
Iwanami, M. et al., Chem. Pharm. Bull., 27 1426-40 (1974).
Eisner, et al., Chem. Rev. 72, 1-53 (1972). Sausins, A. et al., Khim Geterolsike Soedin, 493-501 (1980).
Wilson, J. D. et al., J. Org. Chem., vol. 35, No. 5, (May 1970) pp. 1542-1545.

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