Process and reagent for the determination of the biological acti

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor

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435 23, 435810, C12Q 156, C12Q 138

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active

044093276

ABSTRACT:
Method and reagent for the determination of the biological activity of heparin in plasma by adding thrombin or Factor X.sub.a as the proteolytic enzyme and a chromogen substrate of the latter and measuring the dye liberated from the chromogen substrate in the absence of exogenous anti-thrombin III, the improvement consisting of adding, additionally, at least one compound of the formula ##STR1## wherein X is oxygen or the group NR.sub.5 ;

REFERENCES:
patent: 4191808 (1980-03-01), Nagatsu et al.
patent: 4234682 (1980-11-01), Bartl et al.
patent: 4247454 (1981-01-01), Ekenstam et al.

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