Process and kit for determining blood platelet stress

Details Process and kit for determining blood platelet stress Process and kit for determining blood platelet stress

1984-06-22

1986-07-15

Schor, Kenneth M.

Chemistry: analytical and immunological testing

Biological cellular material tested

436 92, 436 98, 436161, G01N 3348

Patent

active

046006966

ABSTRACT:
A process and kit are provided for measuring chemical and physical stresses on the blood platelets of a human patient by measuring reduction in ATP (adenosine triphosphate) and ADP (adenosine diphosphate) concentrations while measuring increases in the ATP degradation products HYPX (hypoxanthine) and AMP (adenosine monophosphate). The process is useful for measuring a human patient's risk to internal stress such as reduction in the size of blood vessels, to response to various environmental changes as well as to a variety of treatments including drug treatment, risk of malignant hyperthermia in response to anesthetic administration or in response to vascular or organ transplant.

REFERENCES:
patent: 3615224 (1971-10-01), Stern et al.
Tood-Sanford, Clinical Diagnosis by Laboratory Methods; 15th Edition; Edited by Davidson and Henry; 1974; W. B. Saunders Company, Philadelphia, Pa., pp. 303, 416.
Gradwohl's Clinical Laboratory Methods and Diagnosis; Edited by Sonnenworth and Jarett; Eighth Ed.; 1980, The C. V. Mosby Company, St. Louis, Mo.; pp. 1002-1012.

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