Process and intermediates for the manufacture of pyridine-2,3-di

Details Process and intermediates for the manufacture of pyridine-2,3-di Process and intermediates for the manufacture of pyridine-2,3-di

1999-06-15

2000-06-27

Davis, Zinna Northington

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21380

Patent

active

060808675

ABSTRACT:
The present invention provides a process to prepare a pyridine-2,3-dicarboxylate derivative via the reaction of a dialkyl alkoxy(or alkylthio)oxalacetate with an appropriately substituted acrolein compound in the presence of an ammonia source and a solvent.
The present invention also provides useful intermediate compounds of formula IV. ##STR1##

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patent: 4973695 (1990-11-01), Yamashita et al.
patent: 5008392 (1991-04-01), Meier et al.
patent: 5047542 (1991-09-01), Gupton et al.
patent: 5101067 (1992-03-01), Meier et al.
patent: 5175300 (1992-12-01), Yamashita et al.
patent: 5252739 (1993-10-01), Yamashita et al.

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