Process and intermediates for chiral epoxides

Details Process and intermediates for chiral epoxides Process and intermediates for chiral epoxides

1992-05-12

1993-10-26

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfonate esters

C07C30908

Patent

active

052568075

ABSTRACT:
Chiral epoxybutyrates are prepared in high yield from novel dihydro-3R-substituted sulfonyloxy-4R-hydroxy-2-(3H)furanones via based catalyzed alcoholysis. The product chiral epoxy butyrates are useful intermediates for the synthesis of 1-carba-1-dethia cephem antibiotics.

REFERENCES:
Percy S. Manchand et al., "A Novel Synthesis of the Monobactam Antibiotic Carumonam", J. Org. Chem. 53, 5507-5512 (1988).
Seiki Saito et al., "Novel Approach to Stereoisomerically Full Set of Optically Pure 2,3-Epoxyesters from Tartaric Acids", Tetrahedron Letters, vol. 27, No. 43, 5249-5252 (1986).

Affiliated with

Also associated with

Rating

Process and intermediates for chiral epoxides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process and intermediates for chiral epoxides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process and intermediates for chiral epoxides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-960527