Process and intermediates for 3-heteroaryl-4(3H) quinazolines

Details Process and intermediates for 3-heteroaryl-4(3H) quinazolines Process and intermediates for 3-heteroaryl-4(3H) quinazolines

1999-08-16

2000-08-01

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21170, C07D21182, C07D21346

Patent

active

060968931

ABSTRACT:
A new pyridine carbaldehyde is useful for the synthesis of compounds which are effective for treating neurodegeneration conditions and CNS trauma.

REFERENCES:
CAS printout for WO 93/20053, Oct. 1993.
Tetrahedron Letters, vol. 37, No. 15, pp. 2537-2540, 1996, Cai, et al, "A Study of the Lithiation of 2,6-Dibromopyridine with Butyllithium, and its Application to Synthesis of L-739,010".
Inorganic Chemistry, vol. 10, No. 11, pp. 2472-2478, 1971, Parks, et al, "Three-Dimensional Macrocyclic Encapsulation Reactions. II..sup.1 Synthesis and Properties of Nonoctahedral Clathro Chelates Derived from Tris(2-aldoximo-6-pyridyl)phosphine and Boron Trifluoride or Tetrafluoroborate".
J. Org. Chem. 1997, 62, 8237-8239, Peterson, et al, "Efficient Preparation of 2-Bromo-6-lithiopyridine via Lithium-Bromine Exchange in Dichloromethane".

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