Process and intermediate for preparation of donepezil

Details Process and intermediate for preparation of donepezil Process and intermediate for preparation of donepezil

2007-01-03

2011-10-04

Desai, Rita (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S189000

Reexamination Certificate

active

08030491

ABSTRACT:
The invention relates to new compounds of formula (III):wherein R is a C1-C4linear or branched alkyl group.The invention also relates to new compounds of formula (IV)wherein M is a metal.The invention also relates to methods of making compounds of formulas (III) and (IV) and to methods of making donepezil and pharmaceutically acceptable salts thereof, such as donepezil hydrochloride, using the compounds.

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Foreign communication from a related counterpart application—International Search Report and Written Opinion PCT/GB/2007/000009, Mar. 1, 2007, 12 pages.
Foreign communication from the priority application—International Preliminary Report on Patentability, PCT/GB2007/000009, Jul. 8, 2008, 6 pages.

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