Process and intermediate

Details Process and intermediate Process and intermediate

2007-05-15

2011-11-22

Wilson, James O (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C544S284000

Reexamination Certificate

active

08063210

ABSTRACT:
The invention relates to a new process useful in the preparation of pharmaceutical compounds such as 2-{ethyl[3-({4-[(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)amino]quinazolin-7-yl}oxy)propyl]amino}ethyl dihydrogen phosphate (AZD1152) and intermediates used therein.

REFERENCES:
patent: 2004/058752 (2004-07-01), None
patent: 2004/058781 (2004-07-01), None
patent: WO 2004058781 (2004-07-01), None
patent: 2004/094410 (2004-11-01), None
patent: 2004/105764 (2004-12-01), None
Jung et al, “Discovery of Novel and potent Thiazoloquinazolines as selective Aurora A and B Kinase Inhibitors”, J Med Chem, Jan. 10, 2006, pp. 955-970, vol. 49.

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