Process and device for the laser desorption of an analyte molecu

Radiant energy – Ionic separation or analysis – Methods

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250288, 250423P, B01D 5944, H01J 4900

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active

051189372

ABSTRACT:
The invention relates to a process for the laser desorption of analyte molecular ions, especially of biomolecules, from a specimen. The object of the invention is to improve a process of this type in such a way that intact desorption of biomolecules, preferably of large molecular mass, is also possible with a laser. This is achieved by using laser light of a wavelength of about 300 nm or greater than 300 nm and using a matrix which is able to absorb in the selected wavelength range.

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"Liquid Chromatographic Assay for the Measurement of Glucuronidation of Arylcarboxylic Acids Using Uridine Diphospho-[U-.sup.14 C]Glucuronic Acid", Hansen et al., Journal Chromatogra Biomed. Appl., 1986, 383(1) pp. 51-60.

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