Process and composition for the production of suppositories

Details Process and composition for the production of suppositories Process and composition for the production of suppositories

1976-11-15

1979-04-24

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

128271, 264 5, 264126, 424 14, 424 78, 424358, 424362, 424365, A61K 902

Patent

active

041512740

ABSTRACT:
Disclosed are a composition and process for the production of suppositories wherein a mixture comprising at least one ester out of the group of glycols preferably 1,2-propyleneglycol esterified with one saturated higher fatty acid such as myristic, palmitic and stearic acid and at least one pharmacologically active ingredient is formed, this mixture then is granulated with a solution of at least one film-forming polymer and the resulting granulate is pressed into suppositories on a tableting machine.

REFERENCES:
patent: 2820741 (1958-01-01), Endicott et al.
patent: 2975099 (1961-03-01), Goyan et al.
patent: 3102845 (1963-09-01), Fennell
patent: 3121663 (1964-02-01), Parker
patent: 3133863 (1964-05-01), Tansey
patent: 3136692 (1964-06-01), Bandelin
patent: 3234091 (1966-02-01), Lang et al.
patent: 3266992 (1966-08-01), DE Jong
patent: 3632778 (1972-01-01), Sheth et al.
patent: 3679794 (1972-07-01), Bentholm et al.
patent: 3826823 (1974-07-01), O'Rourke et al.

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