Process and composition for the development of controlled releas

Details Process and composition for the development of controlled releas Process and composition for the development of controlled releas

1993-05-04

1994-10-25

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424470, 424490, 424497, A61K 914

Patent

active

053587235

ABSTRACT:
Gemfibrozil formulations prepared from a single granulation of gemfibrozil and a release-control agent are disclosed. The release-control agent is present in an amount sufficient to provide both immediate and controlled release of gemfibrozil. A method of preparing the formulation and a compressed tablet are also disclosed.

REFERENCES:
patent: 4810501 (1989-03-01), Ghebre-Sellassie
patent: 4925676 (1990-05-01), Ghebre-Sellassie
patent: 4927639 (1990-05-01), Ghebre-Sellassie
patent: 4971804 (1990-11-01), Ghebre-Sellassie
patent: 5102668 (1992-04-01), Eichel et al.
Chemical Abstracts, vol. 80, No. 2, 10 Jul. 1958, Columbus, Ohio; abstract No. 12095k, Nixon, J. R. et al. "Release of Drugs from Suspended and Tabletted Microcapsules," p. 367; col. 2.

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