Process and composition for preparing D-aspartic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435232, 435280, C12P 1320

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active

058342591

ABSTRACT:
A process and composition for preparing D-aspartic acid and .beta.-alanine from D,L-aspartic acid, wherein a solution of D,L-aspartic acid or a salt thereof is contacted with a composition having an L-aspartate-.alpha.-decarboxylase activity of greater than 100 .mu.mol L-aspartate used per hour per gram of cells, under appropriate conditions to produce D-aspartic acid and .beta.-alanine.

REFERENCES:
APS Japanese ABS J62-87088 (Apr. 21, 1997) Koyama et al.
Williamson, J. M. and Brown, G. M., J. Biol. Chem., vol. 254, No. 16, pp. 8074-8082 (1979).
Nakano, Y. and Kitaoka, S., J. Biochem., vol. 70, pp. 327-334 (1971).
Cronan, J. E., Jr., J. Bacteriol., vol. 141, No. 3, pp. 1291-1297 (1980).
Cronan, J. E., Jr., Anal. Biochem., vol. 103, No. 2, pp. 377-380 (1980).
Merkel, W. K. and Nichols, B. P., FEMS Microbiol. Lett., vol. 143, No. 2-3 pp. 247-252 (1996).

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