Process and composition for oral hygiene

Details Process and composition for oral hygiene Process and composition for oral hygiene

1993-10-13

1995-04-04

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

424 52, 424 56, 424 49, A61K 722, A61K 724, A61K 716

Patent

active

054035791

ABSTRACT:
A process for enhancing oral hygiene by reducing oral microflora and for inhibiting the formation of dental plaque in a subject by applying to the oral cavity a composition containing 0.1 to 40 parts, by weight, of a higher alkyl-N-sulfobetaine having the structure ##STR1## where R is a higher alkyl group of from 10 to 18 carbon atoms and b) 0.1 to 40 parts, by weight, of a higher alkyl-N,N-dimethylamine oxide, a higher alkyl-N,N-dihydroxylethylamine oxide, or an acylamide t-amine oxide having the respective structures: ##STR2## wherein R is a higher alkyl of from 10 to 18 carbon atoms, or mixtures of said amine oxides.

REFERENCES:
patent: 3898186 (1975-08-01), Mermelstein
patent: 4207198 (1980-06-01), Kenkare
patent: 4439355 (1984-03-01), Kenkare
patent: 4839158 (1989-01-01), Michaels
patent: 5275804 (1994-01-01), Michaels
Tanzer et al., Antimicrobial Agents and Chemotherapy, vol. 13, No. 6, 1044-1045, Jun. 1978.
Corner, A. M. et al. Abstract 407 Journal of Dental Research vol. 65 Special Issue 1986.
Loe, J. Periodontal Research, 11:135-144 (1976).
Chemical Abstract 100(15):116 324w (1984).
Chemical Abstract 99(13):98853x (1983).
Chemical Abstracts 111:99431m (1989).
Chemical Abstracts 115: 150372e (1991).
Accepted Dental Therapeutics, American Dental Associates, Chicago, 1979, pp. 268-269.

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