Process and composition for determining the activity of creatine

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1951035A, 1951035R, 424 12, G01N 3300, G01N 3114

Patent

active

040677753

ABSTRACT:
A process for determination of CK-MB activity in a sample of a body fluid comprising the steps of incubating the sample, optionally in the presence of CK substrates, with antibodies which inhibit enzymatic activity of the M subunit in CK isoenzymes MM and MB without inactivating enzymatic activity of the B subunit in any CK-MB which may be present and determining the activity of the CK B subunit in the resultant sample.

REFERENCES:
patent: 3932221 (1976-01-01), Pfleiderer
patent: 3994783 (1976-11-01), Rao et al.
Wreton et al., Clinica Chimica Acta, 58(1975) pp. 223-232.
Samuels, Annals New York Academy of Sciences, vol. 103, pp. 858-889 (1963).

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