Liquid purification or separation – Processes – Chromatography
Patent
1986-04-28
1988-02-09
Therkorn, Ernest G.
Liquid purification or separation
Processes
Chromatography
2101982, B01D 1508
Patent
active
047240814
ABSTRACT:
A separation process by liquid chromatography, which comprises sending a mixture sample in a large amount together with a liquid mobile phase to at least one column, into which a packing having a large particle size has been charged, to preliminarily fractionate the components of the mixture, taking out fractions containing objective components from the eluate from the first column, and recycling said fractions within a loop provided with at least one second column, into which a packing having a large particle size has been charged, to separate precisely the objective components.
According to this process, it is possible to separate economically objective components from the sample loaded in a large amount.
REFERENCES:
patent: 3458437 (1969-07-01), Ouano
patent: 3686117 (1972-08-01), Lauer
patent: 4204952 (1980-05-01), Snyder
patent: 4267054 (1981-05-01), Yoritomi
patent: 4274967 (1981-06-01), Snyder
patent: 4314823 (1982-02-01), Rich
patent: 4454043 (1984-06-01), Ting
patent: 4551288 (1985-11-01), Kelly
Kirkland, Introduction to Modern Liquid Chromatography, John Wiley & Sons, Inc., New York, 1979, pp. 519-520.
Ishii Shuji
Kawahara Akio
Saito Hiroshi
Sugeno Hiroto
Soken Kagaku Kabushiki Kaisha
Therkorn Ernest G.
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