Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1990-06-29
1991-12-31
Jones, W. Gary
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
210651, 210655, 210 3264, 210335, 210446, 21050029, 210506, 422 1, 422101, 435311, 935 19, B01D 2500, B01D 6308, B01D 7110
Patent
active
050769332
ABSTRACT:
A single filtration device containing coated filter membranes and absolute pore filters is provided in which the membranes and absolute pore filters are present in two sections of the filter device. The filter device will remove viruses, as modeled by type-C Xenotropic retrovirus, with an efficiency of at least 4.6.times.10.sup.5 ; remove DNA from levels of 10 .mu.g/sample to levels below 10 picograms per 500 mg sample of monoclonal antibody; and will remove at least 97% of some bacterial endotoxins.
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G. Sofer, "Chromatographic Removal of Pyrogens", Biotechnology, Dec., 1984, p. 1035 et seq.
Gerba et al., "Applied & Environmental Microbioogy": 50:1375-1377 (1985).
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Butchko Gregory
Glenn Stephan D.
O'Connell Edward
Smariga Paulette
Cass Myron C.
Coulter Corporation
Jones W. Gary
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