Process and apparatus for producing immobilized enzyme granules

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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435178, 435182, 435288, C12N 1102, C12N 1110, C12N 1104, C12M 140

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active

048001600

ABSTRACT:
Enzyme-containing granules are produced by forming drops of a gellable enzyme-containing liquid with a rotating disc and bringing the drops in contact with a gelling solution. The disc is preferably contained in a column, and the gelling solution flows down walls of the column to a reservoir in a lower legion of the column. Drops of the enzyme-containing liquid from the rotating disc contact the gelling solution while flowing down the walls and are carried to the reservoir. Preferably, the enzyme-containing liquid is an aqueous alginate solution containing the enzyme and the gelling solution is an aqueous calcium chloride solution.

REFERENCES:
patent: 3499745 (1970-03-01), Plumat
patent: 4138292 (1979-02-01), Chibata et al.
patent: 4218409 (1980-08-01), Dannelly
patent: 4386895 (1983-06-01), Sodickson
patent: 4391909 (1983-07-01), Lim
patent: 4613076 (1986-09-01), Dietz et al.

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