Process and apparatus for freezing living cells

Details Process and apparatus for freezing living cells Process and apparatus for freezing living cells

1980-02-27

1982-05-04

Davis, Albert W.

Heat exchange

Regenerator

Checker brick structure

165 12, 165 30, 62 62, 62 78, 62157, 236 78B, F25B 1300

Patent

active

043277993

ABSTRACT:
The process for freezing cell suspensions by locating the suspension in a freezing chamber and simultaneously monitoring the temperature of the suspended cells and of the chamber. The cooling of the chamber is regulated at predetermined rates in response to give temperature levels of the sample. The cooling chamber includes a fan, a heater, and a source of refrigerant. The process includes the steps of selectively decreasing and increasing the temperature of the freezing chamber responsive to predetermined temperature points on the freezing curve of the cell sample.

REFERENCES:
patent: 2964920 (1960-12-01), Staebler
patent: 3875754 (1975-04-01), Faust et al.
patent: 4004975 (1977-01-01), Lionetti et al.
patent: 4018911 (1977-04-01), Lionetti et al.
patent: 4030314 (1977-06-01), Strehler et al.
patent: 4059967 (1977-11-01), Rowe et al.
patent: 4107937 (1978-08-01), Chmiel
patent: 4117881 (1978-10-01), Williams et al.
patent: 4199022 (1980-04-01), Senkan et al.
patent: 4199954 (1980-04-01), McGill
patent: 4251995 (1981-02-01), Pert et al.

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