Package making – Methods – With contents treating
Patent
1981-12-17
1983-02-08
Culver, Horace M.
Package making
Methods
With contents treating
53469, 53474, 53512, 128214R, 141105, 141286, 366162, 366173, 366174, 366337, B65B 306, B65B 326
Patent
active
043721001
ABSTRACT:
A process and apparatus for mixing at least two parenteral solutions, sterilizing the resulting mixture, and transferring the sterilized mixture into an extensible, plastic receiving bag. The apparatus includes a mixing chamber into which the solutions can be delivered, a bacterial organism retentive filter for sterilizing the mixture of the solutions received from the chamber, such a receiving bag, tubing for transferring each of the solutions to be chamber, and second tubing for transferring the sterilized mixture from the filter to the bag. All are combined and then sterilized as a unit. In one embodiment of the invention, the bag is placed in a vacuum chamber to facilitate transfer of the mixture through the apparatus and the mixing chamber has a baffle or system of baffles for creating turbulence in the solutions while they are being mixed. The diameter and length of each tubing leading into the chamber from a solution holding container is preselected with respect to the viscosity of the solution in that holding container, so that both solutions reach the chamber at the same time or in a selected order and are mixed in an equal or preselected proportion therein.
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Hunt and Latiolais, Travenol Laboratories, Inc. Training Manual for Central Intravenous Admixture Personnel (1976), p. 93.
Larson Kenneth W.
Miller Robert A.
Schopen Joseph L.
Baxter Travenol Laboratories Inc.
Culver Horace M.
Gerstman George H.
Kirby, Jr. John P.
Price Bradford R. L.
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