Process and apparatus for carrying out specific binding assays

Details Process and apparatus for carrying out specific binding assays Process and apparatus for carrying out specific binding assays

1987-06-01

1989-12-26

Kepplinger, Esther M.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436531, 436532, 436809, 435 7, 435810, 422 99, G01N 33543, G01N 33545

Patent

active

048898163

ABSTRACT:
An immunoassay for an analyte is disclosed in which (a) sample, (b) an immobilized specific binding partner for the analyte and (c) the specific binding partner for the analyte conjugated to a detectable marker are reacted together in a single step. Competitive interference of the reagents is avoided by using reagent (c) in a slow-release form as a glaze coated on a surface in contact with the reaction liquid.

REFERENCES:
patent: Re29169 (1977-04-01), Schuurs et al.
patent: 3826619 (1974-07-01), Bratu
patent: 4146365 (1979-03-01), Kay et al.
patent: 4234316 (1980-11-01), Hevey
patent: 4244940 (1981-01-01), Jeong et al.
patent: 4361647 (1982-11-01), Remington et al.
Sevier et al, "Monoclonal Antibodies in Clinical Immunology", Clin. Chem., vol. 27, No. 11 (1981), pp. 1797-1806.

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