Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1987-12-03
1988-11-08
Sever, Frank
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
210639, 210641, 210651, 530414, B01D 1300
Patent
active
047832649
ABSTRACT:
A process is disclosed for the recovery of a compound, for example, a peptide-containing compound, from a solution containing contaminants through combined affinity-chromatographic purification and ultrafiltration. The process comprises contacting the solution containing the compound and impurities with a first complex of ligand bound to a carrier so as to form a second complex of the compound, the ligand and the carrier, wherein the carrier is comprised of a macromolecular solid material; subsequently splitting off of the compound from the second complex to reform the compound and first complex; and separating of the compound from the first complex. An arrangement for the recovery of a compound from such a solution containing impurities is also disclosed.
REFERENCES:
patent: 3850798 (1974-11-01), Stoquist
patent: 4039413 (1977-08-01), Kraemer et al.
patent: 4066505 (1978-01-01), Schneider
patent: 4361484 (1982-11-01), Larsson et al.
patent: 4459361 (1984-07-01), Gefter
Mattiasson Bo G.
Nylen Ulf T. G.
Gambro Lundia AB
Sever Frank
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