Process and a device for improved oxygenation of biological cult

Details Process and a device for improved oxygenation of biological cult Process and a device for improved oxygenation of biological cult

1989-04-27

1991-04-16

Wax, Robert A.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

43524025, 435284, 435286, 435315, 435818, C12N 502, C12M 302

Patent

active

050081977

ABSTRACT:
The present invention provides an improved method and apparatus for cultivating mammalian cells. The invention relates to reaction vessels having a mechanical stirrer therein. The improvement comprises supplying oxygen to the culture media in the vessel through at least one oxygen-permeable membrane which is located on the stirrer so that the oxygen permeable membrane provides enhanced oxygen transfer across the membrane which is in contact with the culture media. The method and apparatus provides improved oxygen transfer across the membrane in comparison to other devices in which the oxygen permeable membrane is not located on the stirrer.

REFERENCES:
patent: 3900186 (1975-08-01), Balas
patent: 4596779 (1986-06-01), Ono
patent: 4649114 (1987-03-01), Mittenburger et al.
patent: 4649118 (1987-03-01), Anderson

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