Procedure to prepare a solution with capsaicin

Details Procedure to prepare a solution with capsaicin Procedure to prepare a solution with capsaicin

1999-06-16

1999-11-30

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A61K 3116

Patent

active

059944072

ABSTRACT:
The present invention refers to a procedure to prepare a Capsaicin solution in various steps, preferentially three; the first steps consists in the preparation of the solution "A" by mixing 80 milliliters of saline solution, 10 milliliters of polyoxyenthylenesorbitan monooleate and 10 milliliters of paraffin oil. Later on, the second stage is the preparation of solution "B" by mixing 3 milligrams of 8-Methyl-N-Vanillyl-6-Nonenamide in 100 milliliters of the solution "A". Finally the third stage includes the preparation of solution "C" mixing 10 milliliters of solution "B" in 90 milliliters of solution "A" in order to obtain a 10-micromolar concentration of 8-Methyl-N-Vanillyl-6-Nonenamide.

REFERENCES:
patent: 4997853 (1991-03-01), Bernstein
patent: 5178879 (1993-01-01), Adekunle et al.
patent: 5869533 (1999-02-01), Holt

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