Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1992-05-15
1993-05-25
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
424 11, 436513, 436531, 436821, 436828, G01N 3353, G01N 33555, G01N 33567
Patent
active
052139638
ABSTRACT:
A procedure for finding and identifying red cell antibodies by means of the solid-phase method, comprising contacting erythrocytes having selected antigen patterns with sera or plasmas that are to be tested for antibodies and transferred along with a polyspecific anti-human globulin reagent onto a substrate coated with protein A or protein G, thereby to transfer the detection or identification cells or, in the case of autocontrols, inherent cells.
REFERENCES:
patent: 4328183 (1982-05-01), Rosenfield et al.
patent: 4560647 (1985-12-01), Stocker
patent: 4757002 (1988-07-01), Joo
Transfusion 1990, 30, pp. 114-116, "Solid-phase antiglobulin test for screening and identification of red cell antibodies".
Beck et al., Med. Lab. Sci. 41:374-381, 1984.
Harlow et al., Antibodies: a Laboratory Manual, Cold Spring Laboratory, Cold Spring Harbor, NY, 1988, pp. 23-33.
Biotest Aktiengesellschaft
Kepplinger Esther L.
Wortman Donna C.
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