Procainamide antigen conjugates and antibodies

Details Procainamide antigen conjugates and antibodies Procainamide antigen conjugates and antibodies

1978-05-08

1980-11-25

Schain, Howard E.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

23230B, 260112B, 260112R, 260121, 424 85, 424 88, 435 7, 435190, 562426, 562448, 562450, C07G 700, C07G 702

Patent

active

042359694

ABSTRACT:
Compounds are provided for use in the preparation of reagents which can be used in immunoassays for the determination of benzamides of N,N-dialkylethyleneamines. A linking group is provided, at a particular site of the drug, which provides a link between the above compounds and an antigen, with the resulting conjugate being employed for the preparation of antibodies. The antibodies find particular use in competitive protein binding assays. Conjugates to enzymes are prepared which find particular use in homogeneous enzyme immunoassays.

REFERENCES:
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3843696 (1974-10-01), Wagner et al.
patent: 3875011 (1975-04-01), Rubenstein et al.
patent: 3888866 (1975-06-01), Leute et al.
patent: 4046722 (1977-09-01), Rowland
patent: 4065354 (1977-12-01), Ullman et al.
patent: 4069105 (1978-01-01), Singh
Clin. Chem. 23, pp. 705-708, (1977), Rocco et al.
Clin. Exp. Immunol. (1968), 3, pp. 901-909, Russell et al.
Dictionary of Organic Compounds, 4th Ed., vol. 5, p. 2778, 1965.

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