Probursin

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 11 to 14 amino acid residues in defined sequence

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530333, 530334, 514 14, 525 541, 525 5411, 436 86, A61K 3724, C07K 508, C08F28300

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active

049945548

ABSTRACT:
A multi-functional mammalian peptide probursin isolated in purified form, produced synthetically or recombinantly can be used therapeutically for treatment of immune disorders and tumor inhibition.

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Brand, et al, Science, 193:319-321 (Jul. 23, 1976), [Brand I].
Brand, et al, Nature, 269:597-598 (Oct. 13, 1977) [Brand II].
Goldstein et al, Cold Spring Harbor Symposia on Quantitative Biology, XLI:5-8 (1977) [Goldstein I].
Goldstein, in "Molecular Control of Proliferation and Differentiation", pp. 197-202, Academic Press (1977) [Goldstein II].
Y. Stabinsky et al, Mol. Cell. Biochem., 30:71 (1980).
R. S. Hill et al, Diabetes, 34:115 (1985).
M. J. Berridge et al, Biochem. J., 212:473 (1983).

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