Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2007-03-06
2007-03-06
Marx, Irene (Department: 1651)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C424S093450
Reexamination Certificate
active
10606114
ABSTRACT:
A strain ofLactobacillus salivariusisolated from resected and washed human gastrointestinal tract inhibits a broad range of Gram positive and Gram negative microorganisms and secretes a product having antimicrobial activity into a cell-free supernatant. The activity is produced only by, growing cells and is destroyed by proteinase K and pronase E, the inhibitory properties of the strain and its secretory products being maintained in the presence of physiological concentrations of human bile and human gastric juice. The strain exhibits a broad-spectrum of activity against bacteria includingListeria, Staphylococcus, including methocillin resistantSt. aureus(MRSA), andBacillus, but does not inhibit many closely relatedlactobacilli. An antimicrobial agent is obtained from the strain which has bacteriocin-like properties.
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Collins John Kevin
O'Sullivan Gerald Christopher
O'Sullivan Marian Mary Geraldine
Thornton Gerardine Mary
Birch & Stewart Kolasch & Birch, LLP
Enterprise Ireland
Marx Irene
University College Cork - National University of Ireland
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