Probiotic propionibacterium

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Bacteria or actinomycetales

Reexamination Certificate

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C426S072000, C435S004000

Reexamination Certificate

active

07427397

ABSTRACT:
The present invention relates to probioticPropionibacteriumstrains and their use in the preparation of probiotic supplements and foods. The invention relates to the provision of Vitamin B12, propionic acid, folacin and bacteriocins by probiotic strains, stimulation of bifidobacteria growth, production of favourable effects on the lipid metabolism and on the immune system of hosts through immunostimulation, immunomodulation or use of a probiotic strain as an adjuvant, reduction of homocysteine and β glucuronidase and the prevention, treatment or amelioration of conditions associated with a need for these activities. The probiotic bacteria of the invention can be used in humans or other animals. In at least some applications, the bacteria can be used dead and parts rather than whole cells may be used. The present invention also relates to the preparation of vaccines for use in protecting patients from infectious diseases, in particular tuberculosis.

REFERENCES:
patent: 4210720 (1980-07-01), Kojima et al.
patent: 4981705 (1991-01-01), Tomes
patent: 5639659 (1997-06-01), Barefoot et al.
patent: 5989612 (1999-11-01), King et al.
patent: 6019985 (2000-02-01), Brown et al.
patent: 6080401 (2000-06-01), Reddy et al.
patent: 6262019 (2001-07-01), Keller et al.
patent: 6455063 (2002-09-01), Rehberger et al.
patent: 7270994 (2007-09-01), Jiang et al.
patent: 7279320 (2007-10-01), Parker et al.
patent: 2003/0129165 (2003-07-01), Rehberger et al.
patent: 2004/0028689 (2004-02-01), Borody
patent: 58612/86 (1986-12-01), None
patent: 0914778 (1999-05-01), None
patent: 1060745 (2000-12-01), None
patent: 1308506 (2003-05-01), None
patent: 1374878 (2004-01-01), None
patent: WO-9804275 (1998-02-01), None
patent: WO-0020013 (2000-04-01), None
Adams et al, Proceedings of the Nutrition Society of Australia (2002), vol. 26, p. S261.
Ball, G.F.M., “Bioavailability and Analysis of Vitamins in Foods”, 1998, Chapter 14, pp. 497-515.
Rowland, Ian R., Probiotics: The Scientific Basis, 1992, “Metabolic Interactions in the Gut”, Chapter 3, pp. 29-53.
Carmel, Ralph,“Current Concepts in Cobalamin Deficiency,” Annu. Rev. Med. vol. 51, 2000, pp. 357-375.
Brooker et al, “Adhesion of Lactobacilli to the Chicken Crop epithelium,” Journal of Ultrastructure Research vol. 52, 1975, pp. 21-31.
Schaible et al, “Confrontation between Intracellular Bacteria and the Immune System,” Advances in Immunology vol. 71, pp. 267-377.
Sato et al, “Differential Potentiation of Anti-Mycobacterial Activity and Reactive Nitrogen Intermediate Producing Ability of Murine Peritoneal Macrophages Activated by Interferon-Gamma (IFN-γ) and Tumour Necrosis Factor-Alpha (TNF-α),” Clin Exp. Immunol. vol. 112, 1998, pp. 63-68.
Sarem et al, “Comparison of the Adherence of Three Lactobacillus Strains to Caco-2 and Int-407 Human Intestinal Cell Lines,” Letters in Applied Microbiology vol. 22, 1996, pp. 439-442.
Salminen et al, “Clinical Applications of Probiotic Bacteria,” Int. Dairy Journal vol. 8, 1998, pp. 563-572.
Salminen et al, “Demonstration of Safety of Probiotics—A Review,” International Journal of Food Microbiology vol. 44, 1998, pp. 93-106.
Salminen et al, “Probiotics: How They Should be Defined?” Trends in Food Science & Technology vol. 10, 1999, pp. 107-110.
Wang et al, “The Protective Effects of High Amylose Maize (Amylomaize) Starch Granules on the Survival ofBifidobacteriumspp. in the Mouse Intestinal Tract,” Journal of Applied Microbiology vol. 87, 1999, pp. 631-639.
van der Griend et al, “Hyperhomocysteinaemia as a Cardiovascular Risk Factor: an Update,” The Netherlands Journal of Medicine vol. 56, 2000, pp. 119-130.
Tuomola et al, “Adhesion of Some Probiotic and DairyLactobacillusStrains to Caco-2 Cell Cultures,” International Journal of Food Microbiology vol. 41, 1998, pp. 45-51.
Tuomola et al, “Human Ileostomy Glycoproteins as a Model for Small Intestinal Mucus to Investigate Adhesion of Probiotics,” Letters in Applied Microbiology vol. 28, 1999, pp. 159-163.
Toy et al, “Basic and Clinical Overview of the Mucosal Immune System,” Seminars in Gastrointestinal Disease vol. 7, No. 1, Jan. 1996, pp. 2-11.
Taylor et al, “Effects of Probiotics and Prebiotics on Blood Lipids,” British Journal of Nutrition vol. 80, Suppl. 2, 1998, pp. S225-S230.
Tascon et al, “Protection against Mycobacterium Tuberculosis Infection by CD8+ T Cells Requires the Production of Gamma Interferon,” Infection and Immunity, Feb. 1998, pp. 830-834.
Takeda et al, “Mitogenic Activity of Whole Cells and Cell Wall Components ofLactobacillus acidophilusGroup Lactic acid Bacteria on Murine Spleen and Peyer's Patch Cells,” Milchwissenschaft vol. 52 No. 1, 1997, pp. 21-25.
Sutter, Vera, “Anaerobes as Normal Oral Flora,” Reviews of Infectious Diseases vol. 6 Supplemental 1, Mar.-Apr. 1984, pp. S62-S66.
Steffen et al, “Relationship between Cecal Population Levels of Indigenous Bacteria and Translocation to the Mesenteric Lymph Nodes,” Infection and Immunity, Mar. 1983, pp. 1252-1259.
Somkuti et al, “Cholesterol Uptake byPropionibacterium freudenreichii,” Current Microbiology vol. 20, 1990, pp. 305-309.
Silva et al, “Cytotoxic T Cells and Mycobacteria,” FEMS Microbiology Letters vol. 197, 2001, pp. 11-18.
Sieling et al, “CD1-Restricted T Cell Recognition of Microbial Lipoglycan Antigens,” Science vol. 269, Jul. 14, 1995, pp. 227-230.
Shaw et al, “Plasma Homocysteine Levels in indigenous Australians,” MJA vol. 170, Jan. 4, 1999, pp. 19-22.
Scott, John, “Folate and Vitamin B12,” Proceedings of the Nutrition Society vol. 58, 1999, pp. 441-448.
Scheinbach, Saul, “Probiotics: Functionality and Commercial Status,” Biotechnology Advances vol. 16, No. 3, 1998, pp. 581-608.
Hess et al, “Live Antigen Carriers as Tools for Improved Anti-tuberculosis Vaccines,” FEMS Immunology and Medicine Microbiology vol. 23, 1999, pp. 165-173.
Herbert, Victor, “Vitamin B-12: Plant Sources Requirements and Assay,” Am J Clin Nutr vol. 48, 1988, pp. 852-858.
Havlir et al, “Human Immune Response to Mycobacterium tuberculosis Antigens,” infection and Immunity, Feb. 1991, pp. 665-670.
Havenaar et al, “Selection of Strains for Probiotic Use,” Probiotics: The Scientific Basis Chapter Nine.
Harrigan, Wilkie, “A Scheme for the Identification of Gram-positive Bacteria,” Laboratory Methods in Food Microbiology, Third Edition, Chapter 39.
Guerin, N., “Evaluation of BCG and New Vaccines against Tuberculosis,” Pediatric Pulmonology Supplement 16, 1997, pp. 286-287.
Grant et al, “The Potential ofPropionibacteriumspp. as Probiotics,” Chapter 18, pp. 589-601.
Gilliland et al, “Importance of Bile Tolerance ofLactobacillus acidophilusUsed as a Dietary Adjunct,” J Dairy Sci vol. 67, 1984, pp. 3045-3051.
Harrigan, Wilkie, “Isolation ofPropionibacteriafrom Swiss Cheese,” Laboratory Methods in Food Microbiology Third Edition, p. 266.
Gautier et al, “DNA Fingerprinting of Dairy Propionibacteria Strains by Pulsed-Field Gel Electrophoresis,” Current Microbiology vol. 32, 1996, pp. 17-24.
Gariballa, S.E., “Review Article: Nutritional Factors in Stroke,” British Journal of Nutrition vol. 84, 2000, pp. 5-17.
Gadelle et al, “β-Glucuronidase Activities of Intestinal Bacteria Determined Both in Vitro and In Vivo in Gnotobiotic Rats,” Applied Environmental Microbiology, Mar. 1985, pp. 682-685.
Fujisawa et al, “Influence of Bile Salts on β-Glucuronidase Activity of Intestinal Bacteria,” Letters in Applied Microbiology vol. 22, pp. 271-274.
Fooks et al, “Prebiotics, Probiotics and Human Gut Microbiology,” International Dairy Journal vol. 9, 19

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