Probing of specific nucleic acids

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S091100, C435S287200, C536S023100, C536S024300

Reexamination Certificate

active

07351528

ABSTRACT:
The present invention relates to improved methods for probing of specific nucleic acids using circularizable probes designed such that they report the presence of a target sequence by allowing a detectable moiety to remain bound if an only if the probe has been cyclized in a target-dependent linking reaction. The invention may be used for distinction between sequence specific variations of nucleic acids.

REFERENCES:
patent: 5124246 (1992-06-01), Urdea
patent: 5427930 (1995-06-01), Birkenmeyer
patent: 5643724 (1997-07-01), Fildes
patent: 5871921 (1999-02-01), Landegren
patent: 5952176 (1999-09-01), McCarthy et al.
patent: WO 95/22623 (1995-08-01), None
Nilsson et al., “Padlock Probes: circularizing oligonucleotides for localized DNA detection”, Science, (Sep. 30, 1994), vol. 265, pp. 2085-2088.
Nilsson et al. “Padlock probes: Circulating oligonucleotides for localized DNA detection”, Science vol. 265, pp. 2085-2088.
Stratagene catalog, p. 39.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Probing of specific nucleic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Probing of specific nucleic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Probing of specific nucleic acids will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2799598

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.