Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1989-03-28
1990-10-16
Yarbrough, Amelia B.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 7, 436501, 436800, 436808, 536 27, C12Q 168
Patent
active
049634771
ABSTRACT:
The invention relates to a kit for detecting the presence of a nucleic acid sequence, such as a gene or a gene fragment, in a composition or a specimen supposed to contain it. The kit comprises a probe containing a nucleic acid complementary with the nucleic acid sequence or gene which is sought. The probe bears at least one 7-iodo-N-2-acetylamino-fluorene group covalently fixed at one at least of the bases of this probe.
REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
patent: 4623627 (1986-11-01), Huang et al.
Sage et al., FEBS Letters, vol. 108, No. 1, pp. 66-68 (1979).
Broyde, S. et al., Chem-Biol Interactions 47, 1983, pp. 69-78.
Chemical Abstracts 103, No. 13, Sep. 30, 1985, p. 307, abst. No. 101405m, Tchen, P. et al., "Use of Chemically . . . in Hybridization".
Chemical Abstracts 101, No. 7, Aug. 13, 1984, p. 187, abst. No. 49915v, Heller, E. et al., "Comparative Mutagenesis . . . Configuration".
Broyde et al., Chem-Biol. Interactions 47, 1983, pp. 69-78.
Sage et al., FEBS Letters, vol. 18, No. 1, pp. 66-68.
Institut National de la Sante et de la Researche Medicale
Institut Pasteur
Yarbrough Amelia B.
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