PRO235 polypeptides

Details PRO235 polypeptides PRO235 polypeptides

2007-05-22

2007-05-22

Chen, Stacy B. (Department: 1648)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S351000

Reexamination Certificate

active

10121043

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: WO 99/14328 (1999-03-01), None
Kameyama et al. Identification of Plexin Family Molecules in Mice, Biochemical and Biophysical Research Communications, 1996, 226:396-402.
Winberg et al. Plexin A is a Neuronal Semaphorin Receptor that Controls Axon Guidance, Cell, 1998, 95:903-916.
Database Search, DNA sequence alignments [BLASTN 2.2.1 (Jul. 12, 2001), NCBI] A1-A28.
Database Search, protein sequence alignments [BLASTP 2.2.1 (Jul. 12, 2001), NCBI] B1-B6.
A. Mizutani, et al., “Plexin: A Novel Neuronal Cell Surface Molecule that Mediates Cell Adhesion via a Homophilic Binding Mechanism in the Presence of Calcium Ions,”Neuron—14:1189-1199 (1995).

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