PRO1382 polypeptides

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07375184

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
Ambrosi et al (Biochem. Pharmacol. (2004) 67:621-630).
Rost et al (J. Mol. Biol. (2002) 318(2):595-608).
Ahlgren, Ulf, et al., “β-Cell-specific inactivation of the mouseIpf1/Pdx1gene results in loss of the β-Cell phenotype and maturity onset diabetes”, Genes & Development, vol. 12, pp. 1763-1768, 1998.
Boj, Sylvia F., et al., “A transcription factor regulatory circuit in differentiated pancreatic cells”, PNAS, vol. 98, No. 25, Dec. 4, 2001.
Eto, Yoko, et al., “Anti-Mitogenic Effects of Sarpogrelate In Cultured Rat Mesangial Cells”, Life Sciences, vol. 60, No. 11, pp. PL 193-PL199, 1997.
Kashgarian, Michael, et al., “Mesangium and Glomerular Disease”, Laboratory Investigation, vol. 52, No. 6, pp. 569-571, 1985.
Gohda, Tomohito, et. al., “Dilazep Hydrochloride, an Antiplatelet Drug, Inhibits Lipopolysaccharide-Induced Mouse Mesangial Cell IL-6 Secretion and Proliferation”, Kidney & Blood Pressure Research, vol. 24, pp. 33-38, 2001.
Leibowitz, Gil, et al. IPF1/PDX1 Deficiency and β-Cell Dysfunction inPsammomys obesus, and Animal With Type 2 Diabetes, vol. 50, Aug. 2001.
Mene, Paolo, et al., “Physiology of the Mesangial Cell”, Physiological Reviews, vol. 69, No. 4, Oct. 1989.
Offield, Martin, F., “PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum”, Department of Cell Biology, vol. 122, pp. 983-995, 1996.
Ono, Takahiko, et al., “Broad Antiproliferative Effects of Benidipine on Cultured Human Mesangial Cells in Cell Cycle Phases”, American Journal of Nephrology, vol. 22, pp. 581-586, 2002.
Ruef, Christian, et al., “Interleukin 6 is an autocrine growth factor for mesangial cells”, Kidney International, vol. 38, pp. 249-257, 1990.
Striker, Liliane J., et al., “The Contribution of Glomerular Mesangial Cells to Progressive Glomerulosclerosis”, Seminars in Nephrology, vol. 9, No. 4, pp. 318-328, Dec. 1989.
Wolf, Gunter, et al., “Angiotensin II Stimulates the Proliferation and Biosynthesis of Type 1 Collagen in Cultured Murine Mesangial Cells”, American Journal of Pathology, vol. 140, No. 1, Jan. 1992.
Zalzman, Michal, et al., “Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells”, PNAS, vol. 100, No. 12, Jun. 10, 2003.
Satoh et alJ Endocrinol(1997) 1549) 27-34.
Siemmon et alProc Natl Acad Sci(1985) 82(20) 7145-7148.
Mizuno et alBrain Res(1995) 686(1) 115-118.
Mizuno et alNo To Shinkei(1995) 47(11) 1069-1074.
Yiangou et alJ Neurochem(1989) 53(3) 886-889.
Mugnaini et alSynapse(1988) 2(2) 125-138.
BLASTN 2 2 1 (Jul. 12, 2001), NCBI; DNA 66526.
BLASTP 2.2 1 (Jul. 12, 2001), NCBI, PRO 1382.
Satoh et al.J. Endocrinol.(1997) 1549):27-34.
Slemmon et al.Proc. Natl. Acad. Sci(1985) 82(20):7145-7148.
Mizuno et al.Brain Res.(1995) 686(1):115-118.
Yiangou et al.J. Neurochem(1989) 53(3): 886-889.
Mugnaini et al.Synapse(1988) 2(2):125-138.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

PRO1382 polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with PRO1382 polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and PRO1382 polypeptides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2768674

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.