Pristinamycin derivatives, their preparation and their use

Details Pristinamycin derivatives, their preparation and their use Pristinamycin derivatives, their preparation and their use

1984-07-12

1986-05-20

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

C07K 512

Patent

active

045900043

ABSTRACT:
The invention provides new pristinamycin II.sub.B derivatives of the formula: ##STR1## in which R represents alkylthio substituted by (i) alkylamino or dialkylamino of which the alkyl parts can form a pyrrolidin-1-yl, piperidino, azetidin-1-yl, azepin-1-yl, morpholino, thiomorpholino or piperazin-1-yl ring (optionally substituted by alkyl), or (ii) pyrrolidin-2-yl or pyrrolidin-3-yl, piperidin-2-yl, piperidin-3-yl or piperidin-4-yl, azetidin-2-yl or azetidin-3-yl or azepin-2-yl, azepin-3-yl or azepin-4-yl;

REFERENCES:
J. Preu d'homne P. Tarridec et A. Belloc pp. 585-591 (1967).
Chem. Abstr. vol. 99, (1983) 212905.
Chem. Abstr. vol 76, (1972) 127404.
Chem. Abstr. vol. 63, (1965) 13408.

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