Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-04-27
2000-11-14
Priebe, Scott D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 43525411, 4353201, 435325, 435455, 435471, 536 231, 536 232, 536 234, 536 237, C12N 1531, C12N 1552, C12N 1562, C12N 1563, C07H 2100
Patent
active
061468460
ABSTRACT:
The invention provides priA polypeptides and polynucleotides encoding priA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing priA polypeptides to screen for antibacterial compounds.
REFERENCES:
Ngo et al., "Computational complexity, protein structure prediction, and the Levinthal paradox", in The Protein Folding Problem and Tertiary Structure Prediction, Merz et al. (eds.), Birkhauser Boston: Boston, MA, pp. 433 and 492-495, 1994.
Rudinger, "Characteristics of the amino acids as componants of a peptide hormone sequence", in Peptide Hormones, Parsons (ed.), University Park Press: Baltimore, MD, pp. 1-7, Jun. 1976.
Swissprot Submission, Accession No. P94461, Direct Submission, Nov. 1,1997.
GenBank Submission, Accession No. Y13937, Direct Submission, Mar. 30, 1998.
Eui Hum Lee, et al, "The priA Gene Encoding the Primosomal Replicative n' Protein of Escherichia coli", Proc. Natl. Acad. Sci. USA, vol. 87, pp. 4620-4624, Jun. 1990.
McDevitt Damien
Shilling Lisa K
St. John Annemarie
Warren Richard L
Deibert Thomas S.
Gimmi Edward R.
King William T.
Priebe Scott D.
SmithKline Beecham Corporation
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