Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2007-10-09
2007-10-09
McKane, Joseph K. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C560S061000, C514S717000
Reexamination Certificate
active
10485849
ABSTRACT:
This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism and liver diseases.
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Leeson, Paul et al., “Synthesis of Thyroid Hormone Analogs. Part 1. Preparation of 3′-heteroarylmethyl-3,5-diiodo-L-thyronines Via Phenol-dinitrophenol Condensation and Relationships Between Structure and Selective Thyromimetic Activity,”J. of the Chem. Soc 'y, vol. 12 pp. 3085-3096 (1988).
Brandt Peter
Edvinsson Karin
Gordon Sandra
Koehler Konrad
Malm Johan
Coppins Janet L.
Galletta Elizabeth A.
Garabedian Todd E.
Karo Bio AB
McKane Joseph K.
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