Primate intra-acrosomal sperm antigen for use in a contraceptive

Details Primate intra-acrosomal sperm antigen for use in a contraceptive Primate intra-acrosomal sperm antigen for use in a contraceptive

1995-10-30

1998-05-19

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

424811, 4353441, 435 693, 435721, 530852, 53038815, 53038885, 514843, A61K 3552, A61K 3900, C12P 2108, C07K 1600

Patent

active

057532311

ABSTRACT:
A substantially purified intra-acrosomal primate sperm antigen useful in a contraceptive vaccine is disclosed herein. The antigen remains associated with primate sperm after the acrosome reaction. In particular, it remains associated with the inner and outer acrosomal membranes. Modified antigens and fragments thereof prepared by protein modification techniques are also disclosed as well as methods for purifying and using the antigens. Also disclosed are monoclonal and polyclonal antibodies to the antigen and methods of making and using such antibodies. Methods of use include purification of the antigen or use in various diagnostic techniques. Also disclosed are cDNA, expression vectors, and transformed microorganisms that produce the antigen.

REFERENCES:
Kallajoki et al., International Journal of Andrology., vol. 7., pp. 283-296., Apr. 1984.
Harlow et al., Antibodies A laboratory Manual., Cold Spring Harbor laboratories., 1988.

Affiliated with

Also associated with

Rating

Primate intra-acrosomal sperm antigen for use in a contraceptive does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Primate intra-acrosomal sperm antigen for use in a contraceptive, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Primate intra-acrosomal sperm antigen for use in a contraceptive will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1850376