Primary phosphoramidate internucleoside linkages and oligonucleo

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 6, 436501, 514 44, 536 245, C07H 2100

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active

061404829

ABSTRACT:
The invention provides new primary phosphoramidate internucleoside linkages that are less sterically constrained than existing phosphoramidate linkages, as well as oligonucleotides containing such linkages and processes for making and methods for using such oligonucleotides.

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