Primary cultures of normal and tumoral human ovarian epithelium

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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43524021, C12N 500

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active

057100381

ABSTRACT:
The present invention relates to primary cultures or established cell lines of ovarian epithelium origin which are substantially equivalent to the cells from the original clinical material from which they are derived and can serve as a powerful model in numerous types of studies including the elaboration of a patient-based tumor profile, thereby permitting a more precise and personalized design of an efficacious therapeutic regimen for cancer therapy. The invention further relates to a method to derive primary cell cultures from benign and malignant ovarian tissue and from ascites.

REFERENCES:
Tsoa et al., Experimental Cell Research, 218(2):499-507 (1995).
Lounis et al., Experimental Cell Research, 215(2):303-09 (Dec. 1994).
Auersperg et al., Laboratory Investigation, 71(4):510-18 (Oct. 1994).
Hirte et al., Cancer, 74(3):900-06 (Aug. 1994).
Karlan et al., Gynecologic Oncology, 31(1): 103-12 (1988).
Ishiwata et al., Gynecologic Oncology, 26(3):340-54 (1987).
Vigani et al., Boll. Soc. Ital. Biol. Sper., 66(6):537-42 (1990).
Hills et al., Br. J. Cancer, 59(4):527-34 (1989).
Berkowitz et al., Am. J. Obstet. Gynecol., 146(6):607-12 (1983).
Hirte et al., Proc. Annu. Meet. Am. Assoc. Cancer Res., 34:A219 (1993).
Emons et al, Cancer Research, 53(22):5439-46 (1993).
Maines-Bandiera et al., Biology of Reproduction, 44(Suppl 1), Paper No. 253 (1991).
ATCC Catalogue of Cell Lines & Hybridomas, 7th edition, pp. 148, 238, 243-245, and 272 (1992).
Scully, 1977, Ovarian Tumors--A Review, Am. J. Pathol. 87: 686-720.
Provencher et al., 1993, Gyn. Oncol. 50: 78-83.
Davies et al., 1993, Cancer Res. 53: 2087-2091.
Khokha et al., 1989, Science 243: 947-950.
Ponton et al., 1991, Cancer Res. 51: 2138-2143.
Siemens et al., 1988, J. Cell Physiol. 134:347-351.
Kruk et al. 1990, Lab. Inves. 63: 132-136.
Wigler et al., 1978, Cell 14: 725-731.
Ganly et al., 1991, Nucleic Acids Res. 19: 3757.
Ganly et al., 1991, Nucleic Acids Res. 19: 3760.
Ganly et al., 1992, Genomics 12: 221-228.
Gareau et al., 1988, Nucleic Acids Res. 16: 1223.
Orita et al., 1989, Genomics 5: 874-879.
Ehlen and Dubeau 1990, Oncogene 5: 219-223.
Zheng et al., 1991, Cancer Res. 51: 4045-4051.
Houle et al., 1991, Genes, Chromosomes and Cancer 3: 358-366.
Krueger et al., 1990, EMBO J. 9: 3241-3252.
Latif et al., 1993, Science 260: 1317-1320.
Unemori et al., 1986, J. Cell. Biol. 103: 1021-1031.

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