Primary culture of olfactory neurons

Details Primary culture of olfactory neurons Primary culture of olfactory neurons

1992-10-06

1994-06-07

Naff, David M.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352401, 4352402, 435240243, C12N 500

Patent

active

053189078

ABSTRACT:
Primary cultures of purified olfactory neurons can be stimulated with physiological levels of odorants. The neurons of the cultures express markers characteristic of mature olfactory neurons in vivo, such as vimentin, olfactory marker protein and neuron-specific enolase. The cultures are useful for screening for odorants and antagonists, as well as for biochemical and physiological studies of olfactory transduction.

REFERENCES:
patent: 4963489 (1990-10-01), Naughton et al.
patent: 5217893 (1993-06-01), Ronnett et al.
Hirsch, J. D. and Margolis, F. L. (1979), Brain Res., 161:277-291.
Kleene, S. J. and Gesteland, R. C. (1981), Brain Res., 229-536-540.
Noble, et al., (1984) Neurosci. Letts., 45:193-198.
Gonzales, et al., (1985), J. Neurosci. Methods, 14:77-90.
Ronnett, Hester and Snyder: (1989), Neuroscience Abstracts, 12:749.
Coon, et al., (1989), Proc. Natl. Acad. Sci. USA, 86:1703-1707.
Calof, A. L. and Chikaraishi, D. M. (1989), Neuron, 3:115-127.
Pixley, S. K. and Pun, R. Y. K. (1990), Develop. Brain Res., 53:125-130.

Affiliated with

Also associated with

Rating

Primary culture of olfactory neurons does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Primary culture of olfactory neurons, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Primary culture of olfactory neurons will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-792342