Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1995-06-06
1997-11-04
Smith, Lynette F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4241881, 4241841, 4242041, A61K 39145, A61K 3921, A61K 3912, A61K 3900
Patent
active
056837020
ABSTRACT:
Animals, including humans, are immunized by antigens, for example, the HA antigen of influenza, by first administering to a naive animal a normally strongly-immunogenic form of the antigen, for example, inactivated or attenuated whole cell virus and subsequently administering a normally weakly-immunogenic isolated and purified viral antigen, to achieve an enhanced immune response to the purified viral antigen.
REFERENCES:
patent: 4496538 (1985-01-01), Gordon
patent: 4619828 (1986-10-01), Gordon
patent: 4950480 (1990-08-01), Barber et al.
Brandt, et al, 1990, "Immunogenic Integral Membrane . . . " Infection and Immunity 58(4): 983-991.
Modrow, et al, 1989, "Use of Synthetic Oligopeptides . . . " J. Acquired Imm. Def. 2: 21-27.
Fox, 1994, "No Winners Against AIDS" Biotechnology 12: 128.
Cohen, 1993, "Jitters Jeopardize AIDS Vaccine . . . " Science 262: 980-981.
Balkovic, et al., 1987, "Immunoglobulin G Subclass . . . ", Antiviral Research 8:151.160.
McLaren, et al., 1980, "Comparative Antigenicity and Immunogenicity of A/USSR/77 Influenza Vaccines in Normal and Primed Mice", Infect. and Immunity vol. 28(1):171-177.
Paul, Ed., Fundamental Immunol., (3rd Edition), 1993, Chapter 37, pp. 1312-1322. Attenuated Viral Vaccines.
Pharmaceutical Sciences, 1990, "Influenza Virus Vaccines", pp. 1395-1397.
Butini, et al., 1994, "Comparative Analysis of HIV-Specitic CTL Activity in Lymphoid Tissue and Peripheral Blood", Abstract J306, J. Cell Biochem Supp. 18B.
Haynes, 1993, "Scientific and Social Issues of Human Immunodeficiency Virus Vaccine Development", Science 260:1279-1286.
Becker Robert S.
Erdile Lorne
Ferguson Laura
Harmon Maurice W.
Huebner Robert
Connaught Laboratories Inc.
Smith Lynette F.
LandOfFree
Primary and secondary immunization with different physio-chemica does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Primary and secondary immunization with different physio-chemica, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Primary and secondary immunization with different physio-chemica will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1831095