Preventives/remedies for thickened scar, keloid or chronic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C424S130100, C530S388230

Reexamination Certificate

active

10469158

ABSTRACT:
A pharmaceutical preparation for preventing and/or treating hypertrophic scars, keloid or chronic arthritic diseases comprising as an effective component an erythropoietin antagonist. More specifically, there is provided a pharmaceutical preparation for preventing and/or treating hypertrophic scars, keloid or chronic arthritic diseases comprising as an effective component an erythropoietin antagonist such as an anti-erythropoietin antibody, an erythropoietin receptor protein, etc. This pharmaceutical preparation has excellent prophylactic and/or therapeutic effects on collagenous hyperproliferation such as hypertrophic scars, keloid, etc., or chronic arthritic diseases such as rheumatoid arthritis, etc.

REFERENCES:
patent: 5278065 (1994-01-01), D'Andrea et al.
patent: 5712370 (1998-01-01), Fibi et al.
patent: 10-101574 (1998-04-01), None
patent: 96/08240 (1996-03-01), None
Yukio et al. Proliferative organ disease treatment and improving agent. English Translation of JP 10-101574 (Apr. 21, 1998).
Freshney, Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., New York, p. 4 (1983).
Holmdahl, Dissection of the genetic complexity of arthritis using animal models. Immunology Letters 103:86-91 (2006).
Kannan et al. Animal models of rheumatoid arthritis and their relevance to human disease. Pathophysiology 12:167-181 (2005).

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