Preventives or remedies for psoriasis containing as the...

Details Preventives or remedies for psoriasis containing as the... Preventives or remedies for psoriasis containing as the...

2008-01-22

2008-01-22

Mertz, Prema (Department: 1646)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C424S143100

Reexamination Certificate

active

10399979

ABSTRACT:
A preventive and therapeutic agent for psoriasis comprising an interleukin-6 (IL-6) antagonist such as, for example, an antibody against IL-6 receptor.

REFERENCES:
patent: 5530101 (1996-06-01), Queen et al.
patent: 5888510 (1999-03-01), Kishimoto et al.
patent: 0 399 429 (1990-11-01), None
patent: 0 409 607 (1991-01-01), None
patent: 0 448 181 (1991-09-01), None
patent: 0 617 126 (1994-09-01), None
patent: 0 783 893 (1997-07-01), None
patent: 0 791 359 (1997-08-01), None
patent: WO 94/08574 (1994-04-01), None
patent: WO 96/38481 (1996-12-01), None
patent: WO 97/48728 (1997-12-01), None
Rachel M. Grossman et al., “Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes”,Proc. Natl. Acad. Sci. USA, vol. 86, pp. 6367-6371, Aug. 1989.
Koh Sato et al., “Reshaping a Human Antibody to Inhibit the Interleukin 6-dependent Tumor Cell Growth”,Cancer Research, American Association for Cancer Research, vol. 53, pp. 851-856, Feb. 15, 1993.
Toshio Hirano et al., “Biological and clinical aspects of interleukin 6”,Immunology Today, vol. 11, No. 12, pp. 443-449, Dec. 1, 1990.
Gilhar et al., “In vivo Effects of Cytokines on Psoriatic Skin Grafted on Nude Mice: Involvement of the Tumour Necrosis Factor (TNF) Receptor,” Clin. Exp. Immunol., Blackwell Science, vol. 106, 1996, pp. 134-142.
Ogata et al., Cytokine; esp. IL-6 no Kenkyu no Shinpo to Rinsho Ouyou, Rinsho Byouri, 1999, vol. 47, No. 4, pp. 321-326.
Takagi et al., “Blockage of interleukin-6 Receptor Ameliorates Joint Disease in Murine Collagen-Induced Arthritis,” Arthritis Rheum. 1998, vol. 41, No. 12, pp. 2117-2121.

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