Preventives and remedies for diffuse lung diseases

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...

Reexamination Certificate

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C424S130100, C424S145100, C424S185100, C435S326000, C436S086000, C436S087000, C514S001000, C530S300000, C530S350000, C530S385000, C530S386000, C530S387100, C530S387300, C530S388100, C530S389200

Reexamination Certificate

active

06905684

ABSTRACT:
Preventives and remedies for diffuse lung diseases whereby apoptosis can be inhibited and thus favorable preventive/therapeutic effects can be established.These drugs contain apoptosis-inhibiting substances as the active ingredient.The above apoptosis-inhibiting substances include Fas antagonists and Fas/Fas ligand binding inhibitors such as Fas derivatives and anti-Fas ligand antibodies.

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Hagimoto et al. Apoptosis and Expression of Fas/Fas Ligand mRNA in Bleomycin-induced Pulmonary Fibrosis in Mice. Am. J. Resp. Cell Mol. Biol. 16:91-101, 1997.
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Program of 17th Meeting Japanese Society of Inflammations, p. 130, No. 16 (1996) and concise English translation.

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