Prevention or elimination of mycoplasma contamination of animal

Details Prevention or elimination of mycoplasma contamination of animal Prevention or elimination of mycoplasma contamination of animal

1989-06-27

1991-09-24

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 31535

Patent

active

050514199

ABSTRACT:
A method of preventing or eliminating mycoplasma contamination of animal or plant cell cultures, which comprises adding an anti-mycoplasmally effective amount of 5-amino-7-(2-aminomethylmorpholino)-1-cyclopropyl-6, 8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid or its salt to a culture medium in which animal or plant cells are cultivated; and an agent or a preparation for preventing or eliminating mycoplasma contamination of animal or plant cell cultures, comprising 5-amino-7-(2-aminomethylmorpholino)-1-cyclopropyl-6, 8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid or its salt.

REFERENCES:
patent: 4795751 (1989-01-01), Matsumoto et al.
Barile et al., "Mycoplasma Infection of Cell Cultures", pp. 35-45 (1978) Plenum Press, New York and London.
Egawa et al., Chem. Abstr., vol. 101, No. 25, 17 Dec. 1984, p. 757, Abstract No. 230377m.
Egawa et al., Chem. Abstr., vol. 107, No. 17, 26 Oct. 1987, p. 690, Abstract No. 154215p.
Matsumoto et al., Chem. Abstr., vol. 106, No. 1, 5 Jan. 1987, p. 268 Abstract No. 2758j.

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