Prevention of toxin production using absorbent products

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424404, 424405, 424411, 424446, 604360, 604904, A61F 1302, A61F 1315, A61F 1320, A61L 1516

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active

053893743

ABSTRACT:
Absorbent products, especially catemenial tampons, for absorbing body fluids, such as menstrual fluid, blood and wound exudates, comprise an amount of a compound effective to inhibit the production of Enterotoxin A, Enterotoxin B and/or Enterotoxin C by Staphylococcus aureus bacteria when the products are brought into contact with the bacteria. The compositions of this invention are also useful to inhibit production of Streptococcal pyrogenic exotoxins A, B and C, as well as hemolysins produced by Groups A, B, F and G streptococci in solution as well as being expected to be effective to inhibit such toxin and hemolysin production when used in conjunction with absorbent products. The compound is selected from the group consisting of monoesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; diesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; and mixtures thereof. The monoesters and diesters have at least one hydroxyl group associated with their aliphatic alcohol residue.

REFERENCES:
patent: 3052607 (1962-09-01), Hirsh
patent: 3219525 (1965-11-01), Berkow et al.
patent: 3584119 (1971-06-01), Langley
patent: 3970759 (1976-07-01), Frankenfeld et al.
patent: 4022775 (1977-01-01), Kabara
patent: 4067997 (1978-01-01), Kabara
patent: 4113851 (1978-09-01), Leveen et al.
patent: 4347237 (1982-08-01), Evenstad et al.
patent: 4374522 (1983-02-01), Olevsky
patent: 4393871 (1983-07-01), Vorhauer et al.
patent: 4405323 (1983-09-01), Auerbach
patent: 4413986 (1983-11-01), Jacobs
patent: 4431427 (1984-02-01), Lefren et al.
patent: 4485029 (1984-11-01), Kato et al.
patent: 4551148 (1985-11-01), Riley et al.
patent: 4582717 (1986-04-01), von Bittera et al.
patent: 4585792 (1986-04-01), Jacob et al.
patent: 4722936 (1988-02-01), Jacob
patent: 4722937 (1988-02-01), Jacob et al.
patent: 4769021 (1988-09-01), Kass
patent: 4788060 (1988-11-01), Endicott et al.
patent: 4788180 (1988-11-01), Bloch
patent: 4921694 (1990-05-01), Hoppe et al.
patent: 4981686 (1991-01-01), Hardy
patent: 4997851 (1991-03-01), Isaacs et al.
patent: 5000749 (1991-03-01), Le Veen et al.
EPO Search Report, Application No. 90108100.0, Mar. 19, 1991.
EPO Search Report, Application No. 91118543.7, Feb. 4, 1992.
EPO Search Report, Application No. 91118572.6, Feb. 10, 1992.
Altenbern, Protease Inhibitors Suppress Enterotoxin B Formation By Staphylococcus Aureus, FEMS Microbiology Letters 3 (1978) pp. 199-202.
Ansari et al., Sodium Bicarbonate Sodium Bicarbonate Douchng for Improvement of the Postcoital Test, Fertility and Sterility, vol. 33, No. 6, (Jun. 1980) pp. 608-612.
Flournoy et al., The Role of Lauricidin as an Antimicrobial Agent, Drugs of Today, vol. 21, No. 8, (1985) pp. 373-377.
Gossel, Feminine Hygiene Products: Why Your Advice is Needed, U.S. Pharmacist, (May 1986), pp. 20-27.
Iandolo, Genetic Analysis of Extravellular Toxins of Staphylococcus Aureus, Annu. Rev. Microbiol. (1989) 43: pp. 375-402.
Iandolo et al., Regulation of Staphylococcal Enterotoxin B.sup.1, Infection and Immunity, vol. 16, No. 2 (May 1977), pp. 610-616.
Ibrahim et al., Inhibition of Growth of Staphylococcus Aureus and Enterotoxin-A Production in Cheddar Cheese Prod. with Induced Starter Failure, J. of Food Protec. vol. 44, No. 3, (Mar. 1981) pp. 189-193.
Kabara, Structure-function Relationships of Surfactants as Antimicrobial Agents, J. Soc. Cosmet. Chem., vol. 29, (Nov. 1978), pp. 733-741.
Notermans et al, Effect of Glyceryl Monolaurate on Toxin Production by Clostridium Botulinum in Meat Slurry, J. of Food Safety vol. 3, (1981), pp. 83-88.
Orden et al., Detect. of Staph. Enterotoxin and Toxic Shock Synd. Toxin-1 (TSST-1) by Immunoblot Comb. with a Semiautomated Electrophoresis System, J. of Immuno. Meth. vol. 144, pp. 197-202 (1991).
Reiser et al., Prod. of Toxic Shock Synd. Toxin 1 by Staph. aureus Restricted to Endogenous Air in Tampons, J. of Cl. Microb., vol. 25, No. 8, (Aug. 1987), pp. 1450-1452.
Robbins et al., Produc. of Toxic Shock Synd. Toxin 1 by Staphy. aureus as Determined by Tampon Disk-Membrane-Agar Method, J. of Clin. Microbio., vol. 25, No. 8, (Aug. 1987), pp. 1446-1449.
Schlivert, Staphy. Enterotoxi B and Toxic-Shock Synd. Toxin-1 are Significantly Assoc. with Non-Menstrual TSS, The Lancet, May 17, 1986, vol. 1, pp. 1149-1150, (Abstract).
Schlivert et al., Toxic Shock Synd. Staphylococcus Aureus: Effect of Tampons on Toxic Shock Synd. Toxin 1 Production, Obstetrics & Gynecology, vol. 64, No. 5 (Nov. 1984), pp. 666-671.
Smith et al., Enterotoxin A Synthesis in Staphylococcus aureus: Inhibition by Glycerol and Maltose, J. of Gen. Microbiology, (1986), 132, pp. 3375-3380.
Smith et al., Effect of Glucose Analogs on the Synthesis of Staphylococcal Enterotoxin A, Journal of Food Safety 8, (1987), pp. 139-146.
Strobino et al, Exposure to Contraceptive Creams, jellies and Douches and their Effect on the Zygote, Society for Epidemiologic Research: Abstracts, p. 434.
Tierno et al., In vitro Amplification of Toxic Shock Syndrome Toxin-1 by Intravaginal Devices, Contraception, vol. 31, No. 2 (Feb. 1985), pp. 185-194.
Garbe, et al., Staphy. aureus Isolates from Patients with Nonmenstrual Toxic Shock Synd., JAMA, May 3, 1985, 253 (17) pp. 2538-2542.
Humphreys, et al., Enterotoxin Production by Staphy. aureus Isolates from Cases of Septicaemia and from Healthy Carriers, J. Med. Microbiology, Mar. 1989, 28, (3) pp. 163-172.
Crass, et al., Involvement of Staphy. Enterotoxins in Nonmenstrual Toxic Shock Synd., J. Clin. Microbiol., Jun. 1986, 23, (6), pp. 1138-1139.

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