Prevention of synovial adhesions

Details Prevention of synovial adhesions Prevention of synovial adhesions

1993-11-23

1995-05-02

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

514825, A61K 9127

Patent

active

054117437

ABSTRACT:
Adhesions in synovial capsules are prevented through the administration of liposome intercalated nonsteroidal anti-inflammatory agents.

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Holmlund et al., Arthroscopy of the rabbit temporomandibula joint, (1986) Int. J. Oral Maxillofac. Surg. 15, 170-175.
Wheater et al., Functional Histology, 2nd Edition (1987) Churchill Livingstone, Edinburgh, pp. 64, 65, 158, 204, 297.
Physicians' Desk Reference, 43rd Edition (1989) pp. 1242-1243.
Webster's dictionary, p. 1151, 1984.
International Search Report of PCT/US91/09017 mailed Apr. 16, 1992.
"Intra-articular Liposomal Therapy", Thomas and Phillips, Chapter 21, 1979.
"Use of Hyaluronic Acid Ester Microspheres in the Treatment of Rheumatoid Arthritis" Hume et al., Proceed.Intern.Symp.Control.Rel.Bioact.Mater. 17(1990).

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