Prevention of probe coating on automated analyzers using a non-d

Details Prevention of probe coating on automated analyzers using a non-d Prevention of probe coating on automated analyzers using a non-d

1996-09-12

1998-07-28

Achutamurthy, Ponnathapura

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 75, 435 78, 435 792, 435337, 530380, 5303871, 436500, 436526, 436544, 436 43, G01N 3353, G01N 3502, A61K 3514, C07K 1600

Patent

active

057861536

ABSTRACT:
A method for substantially preventing coating of hydrophobic material on a probe of an automated analyzer during an assay is described. An automated analyzer having a probe is provided. A composition comprising a non-denaturing surfactant and a reagent for use in the assay is provided. The probe is contacted with the composition during the assay such that hydrophobic material is substantially prevented from coating the probe on the automated analyzer. Compositions for preventing such probe coating are also described. Methods and compositions comprising a non-denaturing surfactant for enhancing the stability of reagents used in an assay are also described.

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Campanella et al., Ann.Chim. 74(7-8); 483-497 (1984).
D'Alagni, M. et al., Colloid Polym. Sci. 263 (2); 160-163 (1985).

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