Prevention of loss and restoration of bone mass by certain...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C514S438000, C564S099000, C549S075000

Reexamination Certificate

active

06998423

ABSTRACT:
Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.

REFERENCES:
patent: 3442890 (1969-05-01), Larsen et al.
patent: 3780095 (1973-12-01), Klemm et al.
patent: 3894065 (1975-07-01), Cragoe, Jr. et al.
patent: 3987091 (1976-10-01), Cragoe, Jr. et al.
patent: 3989749 (1976-11-01), Cragoe, Jr. et al.
patent: 3991087 (1976-11-01), Cragoe, Jr. et al.
patent: 3991106 (1976-11-01), Cragoe, Jr. et al.
patent: 4018802 (1977-04-01), Cragoe, Jr. et al.
patent: 4020177 (1977-04-01), Cragoe, Jr. et al.
patent: 4033996 (1977-07-01), Cragoe, Jr. et al.
patent: 4055596 (1977-10-01), Cragoe, Jr. et al.
patent: 4055597 (1977-10-01), Cragoe, Jr. et al.
patent: 4066692 (1978-01-01), Cragoe, Jr. et al.
patent: 4087435 (1978-05-01), Cragoe, Jr. et al.
patent: 4091107 (1978-05-01), Cragoe, Jr. et al.
patent: 4092356 (1978-05-01), Cragoe, Jr. et al.
patent: 4097504 (1978-06-01), Cragoe, Jr. et al.
patent: 4112236 (1978-09-01), Bicking et al.
patent: 4150235 (1979-04-01), Cragoe, Jr. et al.
patent: 4175203 (1979-11-01), Cragoe, Jr. et al.
patent: 4210749 (1980-07-01), Shetty
patent: 4243678 (1981-01-01), Krastinat
patent: 4309559 (1982-01-01), Cliff
patent: 4803197 (1989-02-01), Wasley
patent: 4911888 (1990-03-01), Fikentscher et al.
patent: 5084466 (1992-01-01), Alig et al.
patent: 5140038 (1992-08-01), Witte et al.
patent: 5332730 (1994-07-01), Chan
patent: 5407951 (1995-04-01), Witte et al.
patent: 5605814 (1997-02-01), Abramovitz et al.
patent: 5607978 (1997-03-01), Woodward et al.
patent: 5658897 (1997-08-01), Burk
patent: 5759789 (1998-06-01), Abramovitz et al.
patent: 6020193 (2000-02-01), Prockop et al.
patent: 6150394 (2000-11-01), Watanabe et al.
patent: 6288120 (2001-09-01), Cameron et al.
patent: 6316415 (2001-11-01), Albrecht et al.
patent: 6344485 (2002-02-01), Cameron et al.
patent: 6426359 (2002-07-01), Cameron et al.
patent: 6436914 (2002-08-01), Sher et al.
patent: 6468502 (2002-10-01), Platzek et al.
patent: 6492412 (2002-12-01), Cameron et al.
patent: 6559137 (2003-05-01), Tung et al.
patent: 6573278 (2003-06-01), Mittendorf et al.
patent: 6743929 (2004-06-01), Vazquez et al.
patent: 6803484 (2004-10-01), Aikins et al.
patent: 6822001 (2004-11-01), Schwendner et al.
patent: 632088 (1990-01-01), None
patent: 682026 (1994-03-01), None
patent: 716788 (1997-01-01), None
patent: 897566 (1983-12-01), None
patent: 31853 (1979-01-01), None
patent: 1917006 (1971-01-01), None
patent: 2854932 (1979-07-01), None
patent: 0528172 (1993-02-01), None
patent: 0606046 (1997-10-01), None
patent: 0617009 (1999-09-01), None
patent: 0605193 (2003-03-01), None
patent: 378103 (1972-05-01), None
patent: 1478281 (1977-06-01), None
patent: 1479156 (1977-07-01), None
patent: 2233644 (1991-01-01), None
patent: 50-19756 (1975-03-01), None
patent: WO9108737 (1991-06-01), None
patent: WO9413696 (1994-06-01), None
patent: WO9419367 (1994-09-01), None
patent: WO9506664 (1995-03-01), None
patent: WO9513069 (1995-05-01), None
patent: WO9514666 (1995-06-01), None
patent: WO9534311 (1995-12-01), None
patent: WO9636595 (1996-11-01), None
patent: WO9727174 (1997-07-01), None
patent: WO9827976 (1998-07-01), None
patent: WO9828264 (1998-07-01), None
Beilstein Registry No. 6013696.
Bicking, et al. “11, 12-Secoprostaglandins. 6. Interphenylene Analogues of Acylhydroxyalkanoic Acids and Related Compounds as Renal Vasodilators”,J. Med. Chem. 26, pp. 335-341 (1983).
Beilstein Registry No. 7826067.
Brooke, et al., “Synthesis of Oligomers Related to Nylon 6”,J. Chem. Soc. Perkin Trans. 1, pp. 3371-3379 (1997).
Beilstein Registry No. 2757864 & DE 1917036.
Beilstein Registry No. 2770568 & US 3,780,095.
Beilstein Registry No. 2394026 & DE 2854932.
Beilstein Registry No. 457106.
Beveridge, et al., “The Pschorr Cyclization”,Aust. J. Chem., pp. 1341-1346 (1972).
Beilstein Registry No. 2181238.
Kunieda, et al., “Mild Dehalogenative Reduction of Tri- and Di-halogenomethyl Groups by Nickel Carbonyl”,J.C.S. Chem. Comm., pp. 885-886 (1972).
Regan, et al., “Cloning of a Novel Human Prostaglandin Receptor with Characteristics of the Pharmacologically Defined EP2 Subtype”,Molecular Pharmacology46, pp. 213-220 (1994).
Bolander, et al., “Estrogen Treatment During Fracture Repair Strengthens Healing Callus in an Osteoporotic Model”,38thAnnual Meeting: Orthopaedic Research, Feb. 17-20, 1992, Washington, D.C.
Busetti, et al., “Crystal and Molecular Structure of N-acetyl N-hydroxy α-amino acids”,Recl. Trav. Chim. Pavs-Bas106, pp. 151-156 (1987).
Woodiel, et al., Anabolic Effects of Prostaglandins in Cultured Fetal Rat Calvariae: Structure-Activity Relations and Signal Transduction Pathway,Journal of Bone and Mineral Research11(9), pp. 1249-1255 (1996).
Barker, et al., “Novel Thiophene-based Macrocycles Related to Azacrown Ethers”,J. Chem. Soc, Chem. Commun, pp. 1733-1734 (1993).
Sartori, et al., “Synthesis and activities of new arylsulfonamido thromboxane A2 Receptor Antagonists”,Eur. J. Med. Chem. 28, pp. 625-632 (1993).
Smith, et al., “11,12-Secoprostaglandins. 3. 8-Alkylthio(sulfinyl and sulfonyl)-12-hydroxyalkanoic Acids and Related Compounds”,Journ. Med. Chem. 20(4), pp. 540-547 (1977).
Smith, et al., “Prostaglandin Isosteres. 1. (8-Aza-, 8,10-Diaza-, and 8-Aza-11-thia)-9-oxoprostanoic Acids and Their Derivatives”,Journ. Med. Chem. 20(10), pp. 1292-1299 (1977).
Ludwig, et al., “The Synthesis of Hydroxylamine Derivatives Possessing Hypocholesteremic Activity”,J. Med. Chem. 10, pp. 556-564 (1967).
Jones, et al., “11,12-Secoprostaglandins. 4. 7-(N-Alkymethanesulfonamido)heptanoic Acids”,J. Med. Chem. 20(10), pp. 1299-1304 (1977).
Fukumoto, et al., “Synthesis and Thromboxane A2/Prostaglandin H2 Receptor Antagonistic Activity of Phenol Derivatives”,J. Med. Chem. 35, pp. 2202-2209 (1992).
Billman, et al., “Reduction of Shiff Bases. III. Reduction with Dimethylamine Borane”,J. Organic Chemistry26, pp. 1437-1440 (1961).
Bicking, et al., “11,12-Secoprostaglandins. 1. Acylhydroxyalkanoic Acids Related Compounds”,J. Med. Chem. 20(1), pp. 35-43 (1977).
Bicking, et al., “11,12-Secoprostaglandins. 5. 8-Acetyl- or 8(1-Hydroxyethyl)-12-hydroxy-13-aryloxytridecanoic Acids and Sulfonamide Isosteres as Inhibitors of Platelet Aggregation”,J. Med. Chem. 21(10), pp. 1011-1018 (1978).
Scutt, et al., “PGE2 Induces the Transition from Non-Adherent to Adherent Bone Marrow Mesenchymal Precursor Cells Via a camp/EP2-Mediate Mechanism”,Prostagalandins49, pp. 383-395 (1995).

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