Prevention of calcification and degeneration of biological tissu

Details Prevention of calcification and degeneration of biological tissu Prevention of calcification and degeneration of biological tissu

1996-06-05

1997-07-08

Weiss, John G.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

424569, 424572, 435 11, 435374, 435366, 435371, A61F 210

Patent

active

056455879

ABSTRACT:
The present invention relates to chemical treatment for prevention of calcification and degeneration of biological tissue grafts used as a whole or in a part as heart valve substitutes, substitutes of blood vessel, pericardial substitutes, and surgical membranes for implantation in human. The process includes the steps of treatment of the grafts with partially degraded heparin to prevent the calcification of glutaraldehyde-treated xenografts.

REFERENCES:
patent: 5104787 (1992-04-01), Lindstrom et al.
patent: 5336616 (1994-08-01), Livesey et al.
patent: 5383927 (1995-01-01), De Goicoechea et al.

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