Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai
Patent
1995-11-27
1998-06-09
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ketone doai
514568, 514699, 514717, 514731, A61K 3112, A61K 3111, A61K 31075, A61K 3106
Patent
active
057634963
ABSTRACT:
A method for the prevention and treatment of atherosclerosis and its related diseases in mammals is provided, in which an NADPH oxidase inhibitor is administered to mammals. The NADPH oxidase inhibitor prevents the production of reactive oxygen species upon exposure of endothelial cells to atherogenic LDL levels, resulting in decreased endocytosis and vascular hyperpermeability. Apocynin is a preferred NADPH oxidase inhibitor. Additionally, there is provided a diagnostic method for predicting the risk to an individual of atherosclerotic-related diseases.
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Huang Evelyn
Ivy C. Warren
The Research Foundation of State University of New York
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